Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report

DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but wa...

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Detalles Bibliográficos
Autores principales: Kamar, Francois G, Kairouz, Victor F, Sabri, Alain N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637545/
https://www.ncbi.nlm.nih.gov/pubmed/23557478
http://dx.doi.org/10.1186/2045-3329-3-5
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author Kamar, Francois G
Kairouz, Victor F
Sabri, Alain N
author_facet Kamar, Francois G
Kairouz, Victor F
Sabri, Alain N
author_sort Kamar, Francois G
collection PubMed
description DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but was successfully treated with Sorafenib, which showed unprecedented response.
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spelling pubmed-36375452013-04-27 Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report Kamar, Francois G Kairouz, Victor F Sabri, Alain N Clin Sarcoma Res Case Report DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but was successfully treated with Sorafenib, which showed unprecedented response. BioMed Central 2013-04-04 /pmc/articles/PMC3637545/ /pubmed/23557478 http://dx.doi.org/10.1186/2045-3329-3-5 Text en Copyright © 2013 Kamar et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamar, Francois G
Kairouz, Victor F
Sabri, Alain N
Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title_full Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title_fullStr Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title_full_unstemmed Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title_short Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report
title_sort dermatofibrosarcoma protuberans (dfsp) successfully treated with sorafenib: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637545/
https://www.ncbi.nlm.nih.gov/pubmed/23557478
http://dx.doi.org/10.1186/2045-3329-3-5
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AT kairouzvictorf dermatofibrosarcomaprotuberansdfspsuccessfullytreatedwithsorafenibcasereport
AT sabrialainn dermatofibrosarcomaprotuberansdfspsuccessfullytreatedwithsorafenibcasereport

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