A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

BACKGROUND: Efficient mechanisms for rejoining of DNA double-strand breaks (DSBs) are vital because misrepair of such lesions leads to mutation, aneuploidy and loss of cell viability. DSB repair is mediated by proteins acting in two major pathways, called homologous recombination and nonhomologous e...

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Detalles Bibliográficos
Autores principales: McKinney, Jennifer Summers, Sethi, Sunaina, Tripp, Jennifer DeMars, Nguyen, Thuy N, Sanderson, Brian A, Westmoreland, James W, Resnick, Michael A, Lewis, L Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637596/
https://www.ncbi.nlm.nih.gov/pubmed/23586741
http://dx.doi.org/10.1186/1471-2164-14-251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637596/
https://www.ncbi.nlm.nih.gov/pubmed/23586741
http://dx.doi.org/10.1186/1471-2164-14-251

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