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A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae
BACKGROUND: Efficient mechanisms for rejoining of DNA double-strand breaks (DSBs) are vital because misrepair of such lesions leads to mutation, aneuploidy and loss of cell viability. DSB repair is mediated by proteins acting in two major pathways, called homologous recombination and nonhomologous e...
Autores principales: | McKinney, Jennifer Summers, Sethi, Sunaina, Tripp, Jennifer DeMars, Nguyen, Thuy N, Sanderson, Brian A, Westmoreland, James W, Resnick, Michael A, Lewis, L Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637596/ https://www.ncbi.nlm.nih.gov/pubmed/23586741 http://dx.doi.org/10.1186/1471-2164-14-251 |
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