Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

BACKGROUND: Senescence-accelerated mice (SAM) are a series of mouse strains originally derived from unexpected crosses between AKR/J and unknown mice, from which phenotypically distinct senescence-prone (SAMP) and -resistant (SAMR) inbred strains were subsequently established. Although SAMP strains...

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Detalles Bibliográficos
Autores principales: Tanisawa, Kumpei, Mikami, Eri, Fuku, Noriyuki, Honda, Yoko, Honda, Shuji, Ohsawa, Ikuro, Ito, Masafumi, Endo, Shogo, Ihara, Kunio, Ohno, Kinji, Kishimoto, Yuki, Ishigami, Akihito, Maruyama, Naoki, Sawabe, Motoji, Iseki, Hiroyoshi, Okazaki, Yasushi, Hasegawa-Ishii, Sanae, Takei, Shiro, Shimada, Atsuyoshi, Hosokawa, Masanori, Mori, Masayuki, Higuchi, Keiichi, Takeda, Toshio, Higuchi, Mitsuru, Tanaka, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637625/
https://www.ncbi.nlm.nih.gov/pubmed/23586671
http://dx.doi.org/10.1186/1471-2164-14-248

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