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RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation
BACKGROUND: Recent work has shown that the chaperone resistant to inhibitors of acetylcholinesterase (RIC-3) is critical for the folding, maturation and functional expression of a variety of neuronal nicotinic acetylcholine receptors. α7 nicotinic receptors can only assemble and functionally express...
Autores principales: | Dau, Alejandro, Komal, Pragya, Truong, Mimi, Morris, Geoff, Evans, Gareth, Nashmi, Raad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637639/ https://www.ncbi.nlm.nih.gov/pubmed/23586521 http://dx.doi.org/10.1186/1471-2202-14-47 |
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