Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

Regulatory elements recruit transcription factors that modulate gene expression distinctly across cell types, but the relationships among these remains elusive. To address this, we analyzed matched DNase-seq and gene expression data for 112 human samples representing 72 cell types. We first defined...

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Detalles Bibliográficos
Autores principales: Sheffield, Nathan C., Thurman, Robert E., Song, Lingyun, Safi, Alexias, Stamatoyannopoulos, John A., Lenhard, Boris, Crawford, Gregory E., Furey, Terrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638134/
https://www.ncbi.nlm.nih.gov/pubmed/23482648
http://dx.doi.org/10.1101/gr.152140.112

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