Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation

The detection and quantification of genetic heterogeneity in populations of cells is fundamentally important to diverse fields, ranging from microbial evolution to human cancer genetics. However, despite the cost and throughput advances associated with massively parallel sequencing, it remains chall...

Descripción completa

Detalles Bibliográficos
Autores principales: Hiatt, Joseph B., Pritchard, Colin C., Salipante, Stephen J., O'Roak, Brian J., Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638140/
https://www.ncbi.nlm.nih.gov/pubmed/23382536
http://dx.doi.org/10.1101/gr.147686.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638140/
https://www.ncbi.nlm.nih.gov/pubmed/23382536
http://dx.doi.org/10.1101/gr.147686.112

Ejemplares similares