Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome

The majority of microbial genomic diversity remains unexplored. This is largely due to our inability to culture most microorganisms in isolation, which is a prerequisite for traditional genome sequencing. Single-cell sequencing has allowed researchers to circumvent this limitation. DNA is amplified...

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Detalles Bibliográficos
Autores principales: Fitzsimons, Michael S., Novotny, Mark, Lo, Chien-Chi, Dichosa, Armand E.K., Yee-Greenbaum, Joyclyn L., Snook, Jeremy P., Gu, Wei, Chertkov, Olga, Davenport, Karen W., McMurry, Kim, Reitenga, Krista G., Daughton, Ashlynn R., He, Jian, Johnson, Shannon L., Gleasner, Cheryl D., Wills, Patti L., Parson-Quintana, Beverly, Chain, Patrick S., Detter, John C., Lasken, Roger S., Han, Cliff S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638143/
https://www.ncbi.nlm.nih.gov/pubmed/23493677
http://dx.doi.org/10.1101/gr.142208.112

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