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The MetaboLights repository: curation challenges in metabolomics

MetaboLights is the first general-purpose open-access curated repository for metabolomic studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. Increases in the number of depositions, number of samples per study a...

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Detalles Bibliográficos
Autores principales: Salek, Reza M., Haug, Kenneth, Conesa, Pablo, Hastings, Janna, Williams, Mark, Mahendraker, Tejasvi, Maguire, Eamonn, González-Beltrán, Alejandra N., Rocca-Serra, Philippe, Sansone, Susanna-Assunta, Steinbeck, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638156/
https://www.ncbi.nlm.nih.gov/pubmed/23630246
http://dx.doi.org/10.1093/database/bat029
Descripción
Sumario:MetaboLights is the first general-purpose open-access curated repository for metabolomic studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. Increases in the number of depositions, number of samples per study and the file size of data submitted to MetaboLights present a challenge for the objective of ensuring high-quality and standardized data in the context of diverse metabolomic workflows and data representations. Here, we describe the MetaboLights curation pipeline, its challenges and its practical application in quality control of complex data depositions. Database URL: http://www.ebi.ac.uk/metabolights