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Why Is Saline So Acidic (and Does It Really Matter?)

Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion of normal saline can lead to metabolic acidaemia, yet the link between the acidity of saline solution and the acidaemia it can engender...

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Autor principal: Reddi, Benjamin AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638298/
https://www.ncbi.nlm.nih.gov/pubmed/23630439
http://dx.doi.org/10.7150/ijms.5868
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author Reddi, Benjamin AJ
author_facet Reddi, Benjamin AJ
author_sort Reddi, Benjamin AJ
collection PubMed
description Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion of normal saline can lead to metabolic acidaemia, yet the link between the acidity of saline solution and the acidaemia it can engender is not straightforward. This commentary draws together the known and putative sources of acidity in saline solutions: it turns out that the acidity of saline solution is essentially unrelated to the acidaemia complicating saline infusion.
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spelling pubmed-36382982013-04-29 Why Is Saline So Acidic (and Does It Really Matter?) Reddi, Benjamin AJ Int J Med Sci Short Research Communication Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion of normal saline can lead to metabolic acidaemia, yet the link between the acidity of saline solution and the acidaemia it can engender is not straightforward. This commentary draws together the known and putative sources of acidity in saline solutions: it turns out that the acidity of saline solution is essentially unrelated to the acidaemia complicating saline infusion. Ivyspring International Publisher 2013-04-17 /pmc/articles/PMC3638298/ /pubmed/23630439 http://dx.doi.org/10.7150/ijms.5868 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Short Research Communication
Reddi, Benjamin AJ
Why Is Saline So Acidic (and Does It Really Matter?)
title Why Is Saline So Acidic (and Does It Really Matter?)
title_full Why Is Saline So Acidic (and Does It Really Matter?)
title_fullStr Why Is Saline So Acidic (and Does It Really Matter?)
title_full_unstemmed Why Is Saline So Acidic (and Does It Really Matter?)
title_short Why Is Saline So Acidic (and Does It Really Matter?)
title_sort why is saline so acidic (and does it really matter?)
topic Short Research Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638298/
https://www.ncbi.nlm.nih.gov/pubmed/23630439
http://dx.doi.org/10.7150/ijms.5868
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