BRAF V600E-Negative Hairy Cell Leukaemia

Since the initial report of the BRAF V600E mutation in hairy cell leukemia, numerous investigators have demonstrated the presence of this activating mutation in nearly all cases of this disease. A case of hairy cell leukemia is documented with a classical clinical, morphological, immunophenotypic, a...

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Autores principales: Langabeer, Stephen E., O'Brien, David, McElligott, Anthony M., Lavin, Michelle, Browne, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638549/
https://www.ncbi.nlm.nih.gov/pubmed/23653869
http://dx.doi.org/10.1155/2013/513049
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author Langabeer, Stephen E.
O'Brien, David
McElligott, Anthony M.
Lavin, Michelle
Browne, Paul V.
author_facet Langabeer, Stephen E.
O'Brien, David
McElligott, Anthony M.
Lavin, Michelle
Browne, Paul V.
author_sort Langabeer, Stephen E.
collection PubMed
description Since the initial report of the BRAF V600E mutation in hairy cell leukemia, numerous investigators have demonstrated the presence of this activating mutation in nearly all cases of this disease. A case of hairy cell leukemia is documented with a classical clinical, morphological, immunophenotypic, and cytochemical profile in which the BRAF V600E was not detected. The diagnostic and therapeutic implications are discussed.
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spelling pubmed-36385492013-05-07 BRAF V600E-Negative Hairy Cell Leukaemia Langabeer, Stephen E. O'Brien, David McElligott, Anthony M. Lavin, Michelle Browne, Paul V. Case Rep Hematol Case Report Since the initial report of the BRAF V600E mutation in hairy cell leukemia, numerous investigators have demonstrated the presence of this activating mutation in nearly all cases of this disease. A case of hairy cell leukemia is documented with a classical clinical, morphological, immunophenotypic, and cytochemical profile in which the BRAF V600E was not detected. The diagnostic and therapeutic implications are discussed. Hindawi Publishing Corporation 2013 2013-04-09 /pmc/articles/PMC3638549/ /pubmed/23653869 http://dx.doi.org/10.1155/2013/513049 Text en Copyright © 2013 Stephen E. Langabeer et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Langabeer, Stephen E.
O'Brien, David
McElligott, Anthony M.
Lavin, Michelle
Browne, Paul V.
BRAF V600E-Negative Hairy Cell Leukaemia
title BRAF V600E-Negative Hairy Cell Leukaemia
title_full BRAF V600E-Negative Hairy Cell Leukaemia
title_fullStr BRAF V600E-Negative Hairy Cell Leukaemia
title_full_unstemmed BRAF V600E-Negative Hairy Cell Leukaemia
title_short BRAF V600E-Negative Hairy Cell Leukaemia
title_sort braf v600e-negative hairy cell leukaemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638549/
https://www.ncbi.nlm.nih.gov/pubmed/23653869
http://dx.doi.org/10.1155/2013/513049
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AT lavinmichelle brafv600enegativehairycellleukaemia
AT brownepaulv brafv600enegativehairycellleukaemia

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