Cargando…

The Impact of the Myeloid Response to Radiation Therapy

Radiation therapy is showing potential as a partner for immunotherapies in preclinical cancer models and early clinical studies. As has been discussed elsewhere, radiation provides debulking, antigen and adjuvant release, and inflammatory targeting of effector cells to the treatment site, thereby as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gough, Michael J., Young, Kristina, Crittenden, Marka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638700/ https://www.ncbi.nlm.nih.gov/pubmed/23653658 http://dx.doi.org/10.1155/2013/281958

Ejemplares similares

The TAM family as a therapeutic target in combination with radiation therapy
por: Tormoen, Garth W., et al.
Publicado: (2017)

The paradox of radiation and T cells in tumors
por: Gough, Michael J., et al.
Publicado: (2022)

Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer
por: Medler, Terry R., et al.
Publicado: (2023)

The Peripheral Myeloid Expansion Driven by Murine Cancer Progression Is Reversed by Radiation Therapy of the Tumor
por: Crittenden, Marka R., et al.
Publicado: (2013)

Immune consequences of CT-guided radiation therapy of mouse mammary tumors
por: Gough, Michael J, et al.
Publicado: (2013)

Tumor control by intravenous administration of STING ligand requires combination with precisely timed radiation therapy
por: Baird, Jason, et al.
Publicado: (2015)

Moving beyond the T cell synapse for combination neoadjuvant immunotherapy in head and neck cancer
por: Bell, R. Bryan, et al.
Publicado: (2022)

Expression of NF-κB p50 in Tumor Stroma Limits the Control of Tumors by Radiation Therapy
por: Crittenden, Marka R., et al.
Publicado: (2012)

Programmed cell death-1 blockade in combination with stereotactic radiation in an orthotopic mouse model of hepatocellular carcinoma
por: Friedman, David, et al.
Publicado: (2015)

Improved efficacy of radiation in combination with TGFβ inhibition in a colorectal cancer mouse model
por: Young, Kristina H, et al.
Publicado: (2013)

Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity
por: Zebertavage, Lauren K., et al.
Publicado: (2020)

Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy
por: Young, Kristina H., et al.
Publicado: (2016)

Radiation therapy and vaccination against tumor-specific EGFRvIII effectively clears tumors in a murine model of head and neck squamous cell carcinoma
por: Uhde, Lauren, et al.
Publicado: (2015)

ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control
por: Blair, Tiffany, et al.
Publicado: (2022)

Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity
por: Crittenden, Marka R., et al.
Publicado: (2018)

Role of the immunosuppressive microenvironment in immunotherapy
por: Tormoen, Garth W., et al.
Publicado: (2018)

Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
por: Crittenden, Marka R., et al.
Publicado: (2016)

The Dynamic Entropy of Tumor Immune Infiltrates: The Impact of Recirculation, Antigen-Specific Interactions, and Retention on T Cells in Tumors
por: Blair, Tiffany C., et al.
Publicado: (2021)

A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma
por: Crocenzi, Todd, et al.
Publicado: (2016)

Radiation and immunotherapy: Renewed allies in the war on cancer
por: Seung, Steven K., et al.
Publicado: (2012)

Defining Immunogenic and Radioimmunogenic Tumors
por: Medler, Terry R., et al.
Publicado: (2021)

Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma
por: Gunderson, Andrew J., et al.
Publicado: (2019)

Preparative immunotherapy with anti-OX40 and anti-CTLA4 improves the response to chemotherapy
por: Friedman, David J, et al.
Publicado: (2014)

Listeria monocytogenes-infected human monocytic derived dendritic cells activate Vγ9Vδ2 T cells independently of HMBPP production
por: Alice, Alejandro F., et al.
Publicado: (2021)

STING expression and response to treatment with STING ligands in premalignant and malignant disease
por: Baird, Jason R., et al.
Publicado: (2017)

Correction: STING expression and response to treatment with STING ligands in premalignant and malignant disease
por: Baird, Jason R., et al.
Publicado: (2018)

Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help
por: Medler, Terry R., et al.
Publicado: (2023)

Circulating immune cells in patients with surgically resected nonfunctional pancreatic neuroendocrine tumors
por: Jutric, Zeljka, et al.
Publicado: (2015)

Phase I/II clinical trial of anti-OX40, radiation and cyclophosphamide in patients with prostate cancer: immunological analysis
por: Kovacsovics-Bankowski, Magdalena, et al.
Publicado: (2013)

Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma
por: Leidner, Rom, et al.
Publicado: (2021)

Intratumoral injection of STING ligand promotes abscopal effect
por: Baird, Jason R, et al.
Publicado: (2014)

A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity
por: Zebertavage, Lauren, et al.
Publicado: (2019)

Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?
por: Demaria, Sandra, et al.
Publicado: (2021)

Radiation-induced myeloid leukemia in murine models
por: Rivina, Leena, et al.
Publicado: (2014)

Transcriptional and immunohistological assessment of immune infiltration in pancreatic cancer
por: Bernard, Brady, et al.
Publicado: (2020)

Explant Modeling of the Immune Environment of Head and Neck Cancer
por: Sharon, Shay, et al.
Publicado: (2021)

TGFβ suppresses CD8(+) T cell expression of CXCR3 and tumor trafficking
por: Gunderson, Andrew J., et al.
Publicado: (2020)

Peroxiredoxins in Cancer and Response to Radiation Therapies
por: Forshaw, Tom E., et al.
Publicado: (2019)

Radiation Therapy for Chemotherapy Refractory Gingival Myeloid Sarcoma
por: Lee, Daniel Y., et al.
Publicado: (2021)

Fluorescent tracking identifies key migratory dendritic cells in the lymph node after radiotherapy
por: Blair, Tiffany C, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nrllu478t22c09patkme7atvnk