Two modes of integrin activation form a binary molecular switch in adhesion maturation

Talin-mediated integrin activation drives integrin-based adhesions. Here we examine the roles of two proteins that induce talin–integrin interactions—vinculin and Rap1-GTP-interacting adaptor molecule (RIAM)—in the formation and maturation of integrin-based adhesions. RIAM-containing adhesions are p...

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Detalles Bibliográficos
Autores principales: Lee, Ho-Sup, Anekal, Praju, Lim, Chinten James, Liu, Chi-Chao, Ginsberg, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639047/
https://www.ncbi.nlm.nih.gov/pubmed/23468527
http://dx.doi.org/10.1091/mbc.E12-09-0695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639047/
https://www.ncbi.nlm.nih.gov/pubmed/23468527
http://dx.doi.org/10.1091/mbc.E12-09-0695

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