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Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands

BACKGROUND: The prevalence of severe obesity in children and adolescents is increasing. However, little is known about cardiometabolic risk factors and quality of life of children with severe obesity. Therefore, the aim of this study was to assess the demographic characteristics and the prevalence o...

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Autores principales: Makkes, Sabine, Renders, Carry M, Bosmans, Judith E, van der Baan-Slootweg, Olga H, Seidell, Jacob C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639189/
https://www.ncbi.nlm.nih.gov/pubmed/23607651
http://dx.doi.org/10.1186/1471-2431-13-62
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author Makkes, Sabine
Renders, Carry M
Bosmans, Judith E
van der Baan-Slootweg, Olga H
Seidell, Jacob C
author_facet Makkes, Sabine
Renders, Carry M
Bosmans, Judith E
van der Baan-Slootweg, Olga H
Seidell, Jacob C
author_sort Makkes, Sabine
collection PubMed
description BACKGROUND: The prevalence of severe obesity in children and adolescents is increasing. However, little is known about cardiometabolic risk factors and quality of life of children with severe obesity. Therefore, the aim of this study was to assess the demographic characteristics and the prevalence of cardiometabolic risk factors and quality of life in severely obese children and adolescents undergoing intensive inpatient treatment for obesity. METHODS: Data were collected between August 2009 and April 2011 on 16 children (8-13y) and 64 adolescents (13-19y) with severe obesity (SDS-BMI >= 3.0 or SDS-BMI >= 2.3 and comorbidity) participating in an RCT evaluating two intensive inpatient treatment programs for obesity. Demographic, anthropometric, clinical characteristics and two components of the EuroQol for the assessment of quality of life are described. RESULTS: Eighty percent of participants in this study had at least one cardiometabolic risk factor in addition to severe obesity. Low HDL-cholesterol and hypertension were most prevalent (65.0% respectively 31.2%). The highest significant correlations were found between SDS-BMI and SDS-waist circumference, fasting plasma insulin and HOMA-IR (correlation coefficients respectively 0.80, 0.49, and 0.48). With regard to quality of life, the mean utility score of the participants was 0.79 on a scale of 0.0 to 1.0 on the EuroQol questionnaire and their mean individual valuation was 69.1 on a scale of 0 to100. CONCLUSION: Cardiometabolic risk factors are already highly prevalent in this group of severely obese children and adolescents. The score of 69.1 found for quality of life in this study suggests that participants experience important limitations in their quality of life. However, quality of life is not associated with the prevalence of cardiometabolic risk factors. TRIAL REGISTRATION: Netherlands Trial Register (NTR1678, registered 20-Feb-2009)
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spelling pubmed-36391892013-04-30 Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands Makkes, Sabine Renders, Carry M Bosmans, Judith E van der Baan-Slootweg, Olga H Seidell, Jacob C BMC Pediatr Research Article BACKGROUND: The prevalence of severe obesity in children and adolescents is increasing. However, little is known about cardiometabolic risk factors and quality of life of children with severe obesity. Therefore, the aim of this study was to assess the demographic characteristics and the prevalence of cardiometabolic risk factors and quality of life in severely obese children and adolescents undergoing intensive inpatient treatment for obesity. METHODS: Data were collected between August 2009 and April 2011 on 16 children (8-13y) and 64 adolescents (13-19y) with severe obesity (SDS-BMI >= 3.0 or SDS-BMI >= 2.3 and comorbidity) participating in an RCT evaluating two intensive inpatient treatment programs for obesity. Demographic, anthropometric, clinical characteristics and two components of the EuroQol for the assessment of quality of life are described. RESULTS: Eighty percent of participants in this study had at least one cardiometabolic risk factor in addition to severe obesity. Low HDL-cholesterol and hypertension were most prevalent (65.0% respectively 31.2%). The highest significant correlations were found between SDS-BMI and SDS-waist circumference, fasting plasma insulin and HOMA-IR (correlation coefficients respectively 0.80, 0.49, and 0.48). With regard to quality of life, the mean utility score of the participants was 0.79 on a scale of 0.0 to 1.0 on the EuroQol questionnaire and their mean individual valuation was 69.1 on a scale of 0 to100. CONCLUSION: Cardiometabolic risk factors are already highly prevalent in this group of severely obese children and adolescents. The score of 69.1 found for quality of life in this study suggests that participants experience important limitations in their quality of life. However, quality of life is not associated with the prevalence of cardiometabolic risk factors. TRIAL REGISTRATION: Netherlands Trial Register (NTR1678, registered 20-Feb-2009) BioMed Central 2013-04-22 /pmc/articles/PMC3639189/ /pubmed/23607651 http://dx.doi.org/10.1186/1471-2431-13-62 Text en Copyright © 2013 Makkes et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Makkes, Sabine
Renders, Carry M
Bosmans, Judith E
van der Baan-Slootweg, Olga H
Seidell, Jacob C
Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title_full Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title_fullStr Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title_full_unstemmed Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title_short Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
title_sort cardiometabolic risk factors and quality of life in severely obese children and adolescents in the netherlands
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639189/
https://www.ncbi.nlm.nih.gov/pubmed/23607651
http://dx.doi.org/10.1186/1471-2431-13-62
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