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Comparison of polystyrene nanoparticles and UV-inactivated antigen-displaying adenovirus for vaccine delivery in mice

BACKGROUND: Inert nanoparticles are attracting attention as carriers for protein-based vaccines. Here we evaluate the immunogenicity of the model antigen ovalbumin delivered on polystyrene particles and directly compare particulate delivery with adenovirus-based immunization. FINDINGS: Mice were vac...

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Detalles Bibliográficos
Autores principales:	Johrden, Lena, Tenbusch, Matthias, Lietz, Ruth, Bonsmann, Michael Storcksdieck genannt, Niezold, Thomas, Wildner, Oliver, Bayer, Wibke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639190/ https://www.ncbi.nlm.nih.gov/pubmed/23560981 http://dx.doi.org/10.1186/1743-422X-10-108

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