Ectopic Expression of Homeobox Gene NKX2-1 in Diffuse Large B-Cell Lymphoma Is Mediated by Aberrant Chromatin Modifications

Homeobox genes encode transcription factors ubiquitously involved in basic developmental processes, deregulation of which promotes cell transformation in multiple cancers including hematopoietic malignancies. In particular, NKL-family homeobox genes TLX1, TLX3 and NKX2-5 are ectopically activated by...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Ehrentraut, Stefan, Tomasch, Jürgen, Quentmeier, Hilmar, Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G., MacLeod, Roderick A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639244/
https://www.ncbi.nlm.nih.gov/pubmed/23637834
http://dx.doi.org/10.1371/journal.pone.0061447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639244/
https://www.ncbi.nlm.nih.gov/pubmed/23637834
http://dx.doi.org/10.1371/journal.pone.0061447

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