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Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds

Basic mechanisms by which cellular barriers sense and respond to integrity disruptions remain poorly understood. Despite its tenuous structure and constitutive exposure to disruptive strains, the vascular endothelium exhibits robust barrier function. We show that in response to micrometer-scale disr...

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Detalles Bibliográficos
Autores principales: Martinelli, Roberta, Kamei, Masataka, Sage, Peter T., Massol, Ramiro, Varghese, Laya, Sciuto, Tracey, Toporsian, Mourad, Dvorak, Ann M., Kirchhausen, Tomas, Springer, Timothy A., Carman, Christopher V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639391/
https://www.ncbi.nlm.nih.gov/pubmed/23629967
http://dx.doi.org/10.1083/jcb.201209077