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Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase

In Drosophila peripheral neurogenesis, Notch controls cell fates in sensory organ precursor (SOP) cells. SOPs undergo asymmetric cell division by segregating Numb, which inhibits Notch signaling, into the pIIb daughter cell after cytokinesis. In contrast, in the pIIa daughter cell, Notch is activate...

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Detalles Bibliográficos
Autores principales:	Upadhyay, Alok, Kandachar, Vasundhara, Zitserman, Diana, Tong, Xin, Roegiers, Fabrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639393/ https://www.ncbi.nlm.nih.gov/pubmed/23609534 http://dx.doi.org/10.1083/jcb.201209023

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