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A tumor suppressor role of the Bub3 spindle checkpoint protein after apoptosis inhibition

Most solid tumors contain aneuploid cells, indicating that the mitotic checkpoint is permissive to the proliferation of chromosomally aberrant cells. However, mutated or altered expression of mitotic checkpoint genes accounts for a minor proportion of human tumors. We describe a Drosophila melanogas...

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Detalles Bibliográficos
Autores principales:	Morais da Silva, Sara, Moutinho-Santos, Tatiana, Sunkel, Claudio E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639401/ https://www.ncbi.nlm.nih.gov/pubmed/23609535 http://dx.doi.org/10.1083/jcb.201210018

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