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Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods
The occlusional performance of sole endoluminal stenting of intracranial aneurysms is controversially discussed in the literature. Simulation of blood flow has been studied to shed light on possible causal attributions. The outcome, however, largely depends on the numerical method and various free p...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639637/ https://www.ncbi.nlm.nih.gov/pubmed/23662158 http://dx.doi.org/10.1155/2013/527654 |
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author | Weichert, Frank Walczak, Lars Fisseler, Denis Opfermann, Tobias Razzaq, Mudassar Münster, Raphael Turek, Stefan Grunwald, Iris Roth, Christian Veith, Christian Wagner, Mathias |
author_facet | Weichert, Frank Walczak, Lars Fisseler, Denis Opfermann, Tobias Razzaq, Mudassar Münster, Raphael Turek, Stefan Grunwald, Iris Roth, Christian Veith, Christian Wagner, Mathias |
author_sort | Weichert, Frank |
collection | PubMed |
description | The occlusional performance of sole endoluminal stenting of intracranial aneurysms is controversially discussed in the literature. Simulation of blood flow has been studied to shed light on possible causal attributions. The outcome, however, largely depends on the numerical method and various free parameters. The present study is therefore conducted to find ways to define parameters and efficiently explore the huge parameter space with finite element methods (FEMs) and lattice Boltzmann methods (LBMs). The goal is to identify both the impact of different parameters on the results of computational fluid dynamics (CFD) and their advantages and disadvantages. CFD is applied to assess flow and aneurysmal vorticity in 2D and 3D models. To assess and compare initial simulation results, simplified 2D and 3D models based on key features of real geometries and medical expert knowledge were used. A result obtained from this analysis indicates that a combined use of the different numerical methods, LBM for fast exploration and FEM for a more in-depth look, may result in a better understanding of blood flow and may also lead to more accurate information about factors that influence conditions for stenting of intracranial aneurysms. |
format | Online Article Text |
id | pubmed-3639637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36396372013-05-09 Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods Weichert, Frank Walczak, Lars Fisseler, Denis Opfermann, Tobias Razzaq, Mudassar Münster, Raphael Turek, Stefan Grunwald, Iris Roth, Christian Veith, Christian Wagner, Mathias Comput Math Methods Med Research Article The occlusional performance of sole endoluminal stenting of intracranial aneurysms is controversially discussed in the literature. Simulation of blood flow has been studied to shed light on possible causal attributions. The outcome, however, largely depends on the numerical method and various free parameters. The present study is therefore conducted to find ways to define parameters and efficiently explore the huge parameter space with finite element methods (FEMs) and lattice Boltzmann methods (LBMs). The goal is to identify both the impact of different parameters on the results of computational fluid dynamics (CFD) and their advantages and disadvantages. CFD is applied to assess flow and aneurysmal vorticity in 2D and 3D models. To assess and compare initial simulation results, simplified 2D and 3D models based on key features of real geometries and medical expert knowledge were used. A result obtained from this analysis indicates that a combined use of the different numerical methods, LBM for fast exploration and FEM for a more in-depth look, may result in a better understanding of blood flow and may also lead to more accurate information about factors that influence conditions for stenting of intracranial aneurysms. Hindawi Publishing Corporation 2013 2013-04-15 /pmc/articles/PMC3639637/ /pubmed/23662158 http://dx.doi.org/10.1155/2013/527654 Text en Copyright © 2013 Frank Weichert et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Weichert, Frank Walczak, Lars Fisseler, Denis Opfermann, Tobias Razzaq, Mudassar Münster, Raphael Turek, Stefan Grunwald, Iris Roth, Christian Veith, Christian Wagner, Mathias Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title | Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title_full | Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title_fullStr | Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title_full_unstemmed | Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title_short | Simulation of Intra-Aneurysmal Blood Flow by Different Numerical Methods |
title_sort | simulation of intra-aneurysmal blood flow by different numerical methods |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639637/ https://www.ncbi.nlm.nih.gov/pubmed/23662158 http://dx.doi.org/10.1155/2013/527654 |
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