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Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others
Cellular activity of BM-ca, a novel humanized anti-CD20 antibody, was quantitatively compared with that of two other anti-CD20 antibodies used for clinical practice, rituximab and ofatumumab. The results of a complement-dependent cytotoxicity (CDC) assay revealed that the strongest antibody was ofat...
Autores principales: | Kobayashi, Hideaki, Matsunaga, Yuka, Uchiyama, Yumiko, Nagura, Kenji, Komatsu, Yasuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639652/ https://www.ncbi.nlm.nih.gov/pubmed/23634281 http://dx.doi.org/10.1002/cam4.60 |
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