Cargando…

Optimized formulation of solid self-microemulsifying sirolimus delivery systems

BACKGROUND: The aim of this study was to develop an optimized solid self-microemulsifying drug delivery system (SMEDDS) formulation for sirolimus to enhance its solubility, stability, and bioavailability. METHODS: Excipients used for enhancing the solubility and stability of sirolimus were screened....

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Wonkyung, Kim, Min-Soo, Kim, Jeong-Soo, Park, Junsung, Park, Hee Jun, Cha, Kwang-Ho, Park, Jeong-Sook, Hwang, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639716/
https://www.ncbi.nlm.nih.gov/pubmed/23641156
http://dx.doi.org/10.2147/IJN.S43299