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Optimized formulation of solid self-microemulsifying sirolimus delivery systems

BACKGROUND: The aim of this study was to develop an optimized solid self-microemulsifying drug delivery system (SMEDDS) formulation for sirolimus to enhance its solubility, stability, and bioavailability. METHODS: Excipients used for enhancing the solubility and stability of sirolimus were screened....

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Detalles Bibliográficos
Autores principales:	Cho, Wonkyung, Kim, Min-Soo, Kim, Jeong-Soo, Park, Junsung, Park, Hee Jun, Cha, Kwang-Ho, Park, Jeong-Sook, Hwang, Sung-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639716/ https://www.ncbi.nlm.nih.gov/pubmed/23641156 http://dx.doi.org/10.2147/IJN.S43299

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