Cargando…
Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity
The role of neuroinflammation and the adaptive immune system in PD (Parkinson's disease) has been the subject of intense investigation in recent years, both in animal models of parkinsonism and in post-mortem PD brains. However, how these processes relate to and modulate α-syn (α-synuclein) pat...
Autores principales: | Sanchez-Guajardo, Vanesa, Barnum, Christopher J., Tansey, Malú G., Romero-Ramos, Marina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639751/ https://www.ncbi.nlm.nih.gov/pubmed/23506036 http://dx.doi.org/10.1042/AN20120066 |
Ejemplares similares
-
Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease
por: Sanchez-Guajardo, Vanesa, et al.
Publicado: (2010) -
α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology
por: Christiansen, Josefine R., et al.
Publicado: (2016) -
Microglia Response During Parkinson’s Disease: Alpha-Synuclein Intervention
por: Ferreira, Sara A., et al.
Publicado: (2018) -
α-Synuclein and Noradrenergic Modulation of Immune Cells in Parkinson’s Disease Pathogenesis
por: Butkovich, Laura M., et al.
Publicado: (2018) -
CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology
por: Olesen, Mads N., et al.
Publicado: (2018)