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Krüppel-Like Factor 4 Transcriptionally Regulates TGF-β1 and Contributes to Cardiac Myofibroblast Differentiation

Angiotensin II (Ang II) plays a major role in the pathogenesis of cardiac fibrosis in hypertension. It is known that Ang II induces TGF-β1 expression. How transcription mediates Ang II-induced TGF-β1 expression, as well as its contribution to cardiac fibrosis, is unknown. We studied the role of Krüp...

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Detalles Bibliográficos
Autores principales:	Zhang, Yi, Wang, Ying, Liu, Yan, Wang, Nanping, Qi, Yongfen, Du, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640021/ https://www.ncbi.nlm.nih.gov/pubmed/23646205 http://dx.doi.org/10.1371/journal.pone.0063424

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