Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp

The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F–H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were i...

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Autores principales: Li, Hou-Jin, Chen, Ting, Xie, Ying-Lu, Chen, Wen-Dan, Zhu, Xiao-Feng, Lan, Wen-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640397/
https://www.ncbi.nlm.nih.gov/pubmed/23434797
http://dx.doi.org/10.3390/md11020551
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author Li, Hou-Jin
Chen, Ting
Xie, Ying-Lu
Chen, Wen-Dan
Zhu, Xiao-Feng
Lan, Wen-Jian
author_facet Li, Hou-Jin
Chen, Ting
Xie, Ying-Lu
Chen, Wen-Dan
Zhu, Xiao-Feng
Lan, Wen-Jian
author_sort Li, Hou-Jin
collection PubMed
description The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F–H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines.
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spelling pubmed-36403972013-05-02 Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp Li, Hou-Jin Chen, Ting Xie, Ying-Lu Chen, Wen-Dan Zhu, Xiao-Feng Lan, Wen-Jian Mar Drugs Article The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F–H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines. MDPI 2013-02-22 /pmc/articles/PMC3640397/ /pubmed/23434797 http://dx.doi.org/10.3390/md11020551 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Li, Hou-Jin
Chen, Ting
Xie, Ying-Lu
Chen, Wen-Dan
Zhu, Xiao-Feng
Lan, Wen-Jian
Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title_full Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title_fullStr Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title_full_unstemmed Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title_short Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp
title_sort isolation and structural elucidation of chondrosterins f–h from the marine fungus chondrostereum sp
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640397/
https://www.ncbi.nlm.nih.gov/pubmed/23434797
http://dx.doi.org/10.3390/md11020551
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