New Steroids from the Soft Coral Nephthea chabrolii

A new cytotoxic 19-oxygenated steroid, nebrosteroid Q (1) and two new cytotoxic 19-norergosterols, nebrosteroids R and S (2 and 3) were isolated from the soft coral Nephthea chabrolii collected at San-Hsian-Tai. The structures of nebrosteroids Q–S (1–3) were elucidated by spectral analysis, and thei...

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Autores principales: Wang, Shang-Kwei, Puu, Shyh-Yueh, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640399/
https://www.ncbi.nlm.nih.gov/pubmed/23434799
http://dx.doi.org/10.3390/md11020571
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author Wang, Shang-Kwei
Puu, Shyh-Yueh
Duh, Chang-Yih
author_facet Wang, Shang-Kwei
Puu, Shyh-Yueh
Duh, Chang-Yih
author_sort Wang, Shang-Kwei
collection PubMed
description A new cytotoxic 19-oxygenated steroid, nebrosteroid Q (1) and two new cytotoxic 19-norergosterols, nebrosteroids R and S (2 and 3) were isolated from the soft coral Nephthea chabrolii collected at San-Hsian-Tai. The structures of nebrosteroids Q–S (1–3) were elucidated by spectral analysis, and their cytotoxicity against selected cancer cells as well as antiviral activity against human cytomegalovirus (HCMV) were measured in vitro.
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spelling pubmed-36403992013-05-02 New Steroids from the Soft Coral Nephthea chabrolii Wang, Shang-Kwei Puu, Shyh-Yueh Duh, Chang-Yih Mar Drugs Article A new cytotoxic 19-oxygenated steroid, nebrosteroid Q (1) and two new cytotoxic 19-norergosterols, nebrosteroids R and S (2 and 3) were isolated from the soft coral Nephthea chabrolii collected at San-Hsian-Tai. The structures of nebrosteroids Q–S (1–3) were elucidated by spectral analysis, and their cytotoxicity against selected cancer cells as well as antiviral activity against human cytomegalovirus (HCMV) were measured in vitro. MDPI 2013-02-22 /pmc/articles/PMC3640399/ /pubmed/23434799 http://dx.doi.org/10.3390/md11020571 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Shang-Kwei
Puu, Shyh-Yueh
Duh, Chang-Yih
New Steroids from the Soft Coral Nephthea chabrolii
title New Steroids from the Soft Coral Nephthea chabrolii
title_full New Steroids from the Soft Coral Nephthea chabrolii
title_fullStr New Steroids from the Soft Coral Nephthea chabrolii
title_full_unstemmed New Steroids from the Soft Coral Nephthea chabrolii
title_short New Steroids from the Soft Coral Nephthea chabrolii
title_sort new steroids from the soft coral nephthea chabrolii
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640399/
https://www.ncbi.nlm.nih.gov/pubmed/23434799
http://dx.doi.org/10.3390/md11020571
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