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Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis
BACKGROUND: Previously, we showed that M3 muscarinic receptor (M3R; gene name Chrm3) deficiency attenuates murine intestinal neoplasia, supporting the hypothesis that muscarinic receptors play an important role in intestinal tumorigenesis. METHODS: To test this hypothesis, in the present study we tr...
Autores principales: | Peng, Zhongsheng, Heath, Jonathon, Drachenberg, Cinthia, Raufman, Jean-Pierre, Xie, Guofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640951/ https://www.ncbi.nlm.nih.gov/pubmed/23617763 http://dx.doi.org/10.1186/1471-2407-13-204 |
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