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Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

BACKGROUND: Conventional treatment for locally advanced rectal cancer usually combines neoadjuvant radiochemotherapy and surgery. Until recently, there have been limited predictive factors (clinical or biological) for rectal tumor response to conventional treatment. KRAS, BRAF and PIK3CA mutations a...

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Detalles Bibliográficos
Autores principales:	Derbel, Olfa, Wang, Qing, Desseigne, Françoise, Rivoire, Michel, Meeus, Pierre, Peyrat, Patrice, Stella, Mattia, Martel-Lafay, Isabelle, Lemaistre, Anne-Isabelle, de La Fouchardière, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640970/ https://www.ncbi.nlm.nih.gov/pubmed/23617638 http://dx.doi.org/10.1186/1471-2407-13-200

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