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Kif3a Guides Microtubular Dynamics, Migration and Lumen Formation of MDCK Cells

The microtubular motor Kinesin-2 and its subunit Kif3a are essential for the formation of primary cilia, an organelle implicated in a wide spectrum of developmental abnormalities. Outside cilia, Kinesin-2 mediated transport has been implicated in vesicle and N-cadherin transport, but it is unknown i...

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Detalles Bibliográficos
Autores principales: Boehlke, Christopher, Kotsis, Fruzsina, Buchholz, Bjoern, Powelske, Christian, Eckardt, Kai-Uwe, Walz, Gerd, Nitschke, Roland, Kuehn, E. Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641035/
https://www.ncbi.nlm.nih.gov/pubmed/23658710
http://dx.doi.org/10.1371/journal.pone.0062165