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Dispensing Processes Impact Apparent Biological Activity as Determined by Computational and Statistical Analyses
Dispensing and dilution processes may profoundly influence estimates of biological activity of compounds. Published data show Ephrin type-B receptor 4 IC(50) values obtained via tip-based serial dilution and dispensing versus acoustic dispensing with direct dilution differ by orders of magnitude wit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641061/ https://www.ncbi.nlm.nih.gov/pubmed/23658723 http://dx.doi.org/10.1371/journal.pone.0062325 |