Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer

INTRODUCTION: Breast cancer brain metastases (BCBM) are a challenging consequence of advanced BC. Nanoparticle agents, including liposomes, have shown enhanced delivery to solid tumors and brain. We compared pharmacokinetics (PK) and efficacy of PEGylated liposomal doxorubicin (PLD) with non-liposom...

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Detalles Bibliográficos
Autores principales: Anders, Carey K., Adamo, Barbara, Karginova, Olga, Deal, Allison M., Rawal, Sumit, Darr, David, Schorzman, Allison, Santos, Charlene, Bash, Ryan, Kafri, Tal, Carey, Lisa, Miller, C. Ryan, Perou, Charles M., Sharpless, Norman, Zamboni, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641071/
https://www.ncbi.nlm.nih.gov/pubmed/23650496
http://dx.doi.org/10.1371/journal.pone.0061359

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