Measuring EGFR Separations on Cells with ∼10 nm Resolution via Fluorophore Localization Imaging with Photobleaching

Detecting receptor dimerisation and other forms of clustering on the cell surface depends on methods capable of determining protein-protein separations with high resolution in the ∼10–50 nm range. However, this distance range poses a significant challenge because it is too large for fluorescence res...

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Detalles Bibliográficos
Autores principales: Needham, Sarah R., Hirsch, Michael, Rolfe, Daniel J., Clarke, David T., Zanetti-Domingues, Laura C., Wareham, Richard, Martin-Fernandez, Marisa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641073/
https://www.ncbi.nlm.nih.gov/pubmed/23650512
http://dx.doi.org/10.1371/journal.pone.0062331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641073/
https://www.ncbi.nlm.nih.gov/pubmed/23650512
http://dx.doi.org/10.1371/journal.pone.0062331

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