Cargando…
Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter
Genotype-to-phenotype maps and the related fitness landscapes that include epistatic interactions are difficult to measure because of their high dimensional structure. Here we construct such a map using the recently collected corpora of high-throughput sequence data from the 75 base pairs long mutag...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641078/ https://www.ncbi.nlm.nih.gov/pubmed/23650500 http://dx.doi.org/10.1371/journal.pone.0061570 |