A New Rapid Methodological Strategy to Assess BRCA Mutational Status

Hereditary cancers account for approximately 10 % of breast and ovarian cancers. Mutations of the BRCA1 and BRCA2 genes, encoding two proteins involved in DNA repair, underlie most cases of such hereditary cancers. Women with BRCA mutations develop breast cancer in 50–80 % of cases and ovarian cance...

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Detalles Bibliográficos
Autores principales: Vuttariello, Emilia, Borra, Marco, Calise, Celeste, Mauriello, Elvira, Greggi, Stefano, Vecchione, Aldo, Biffali, Elio, Chiappetta, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641296/
https://www.ncbi.nlm.nih.gov/pubmed/23354980
http://dx.doi.org/10.1007/s12033-012-9646-0

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