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Potential for therapeutic manipulation of the UPR in disease
Increased endoplasmic reticulum (ER) stress and the activated unfolded protein response (UPR) signaling associated with it play key roles in physiological processes as well as under pathological conditions. The UPR normally protects cells and re-establishes cellular homeostasis, but prolonged UPR ac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641308/ https://www.ncbi.nlm.nih.gov/pubmed/23572207 http://dx.doi.org/10.1007/s00281-013-0370-z |