Cargando…

The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis

The gastrointestinal (GI) epithelium is constantly renewing, depending upon the intestinal stem cells (ISC) regulated by a spectrum of transcription factors (TFs), including Myb. We noted previously in mice with a p300 mutation (plt6) within the Myb-interaction-domain phenocopied Myb hypomorphic mut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sampurno, S, Bijenhof, A, Cheasley, D, Xu, H, Robine, S, Hilton, D, Alexander, W S, Pereira, L, Mantamadiotis, T, Malaterre, J, Ramsay, R G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641342/ https://www.ncbi.nlm.nih.gov/pubmed/23618903 http://dx.doi.org/10.1038/cddis.2013.119

Ejemplares similares

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice
por: Malaterre, J, et al.
Publicado: (2016)

Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation
por: Daniel, P, et al.
Publicado: (2014)

Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse
por: Carpinteri, Sandra, et al.
Publicado: (2015)

Novel Epigenetic CREB-miR-630 Signaling Axis Regulates Radiosensitivity in Colorectal Cancer
por: Zhang, Yan, et al.
Publicado: (2015)

Intestinal Iron Homeostasis and Colon Tumorigenesis
por: Xue, Xiang, et al.
Publicado: (2013)

Therapeutic DNA vaccination against colorectal cancer by targeting the MYB oncoprotein
por: Cross, Ryan S, et al.
Publicado: (2015)

Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms
por: Antony, N., et al.
Publicado: (2016)

Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140
por: Cavaillès, Vincent, et al.
Publicado: (2014)

Src Family Tyrosine Kinases in Intestinal Homeostasis, Regeneration and Tumorigenesis
por: Sirvent, Audrey, et al.
Publicado: (2020)

Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer
por: Millen, Rosemary, et al.
Publicado: (2016)

Experimental study of delivery of humidified‐warm carbon dioxide during open abdominal surgery
por: Carpinteri, S., et al.
Publicado: (2017)

Conformational Control of the Binding of the Transactivation Domain of the MLL Protein and c-Myb to the KIX Domain of CREB
por: Korkmaz, Elif Nihal, et al.
Publicado: (2012)

Transcriptional regulation of autophagy by an FXR/CREB axis
por: Seok, Sunmi, et al.
Publicado: (2014)

Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents
por: Chen, Qingjuan, et al.
Publicado: (2022)

MYB Elongation Is Regulated by the Nucleic Acid Binding of NFκB p50 to the Intronic Stem-Loop Region
por: Pereira, Lloyd A., et al.
Publicado: (2015)

Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice
por: Xu, Huiling, et al.
Publicado: (2010)

Targeting polymerase θ impairs tumorigenesis and enhances radiosensitivity in lung adenocarcinoma
por: Rao, Xinrui, et al.
Publicado: (2023)

Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis
por: Zhang, Zhongwei, et al.
Publicado: (2022)

Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective
por: Tian, Ai, et al.
Publicado: (2018)

JNK-dependent intestinal barrier failure disrupts host–microbe homeostasis during tumorigenesis
por: Zhou, Jun, et al.
Publicado: (2020)

Correction: Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice
por: Xu, Huiling, et al.
Publicado: (2010)

CSF-1 Receptor-Dependent Colon Development, Homeostasis and Inflammatory Stress Response
por: Huynh, Duy, et al.
Publicado: (2013)

p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair
por: Lai, Keane K. Y., et al.
Publicado: (2021)

Circ_0055625 knockdown inhibits tumorigenesis and improves radiosensitivity by regulating miR-338-3p/MSI1 axis in colon cancer
por: Gao, Chao, et al.
Publicado: (2021)

GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis
por: Pu, Yang, et al.
Publicado: (2021)

Roles of Src family kinase, Ras, and mTOR signaling in intestinal epithelial homeostasis and tumorigenesis
por: Matozaki, Takashi, et al.
Publicado: (2020)

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis
por: Jie, Zuliang, et al.
Publicado: (2018)

Natural Products with Antitumor Potential Targeting the MYB-C/EBPβ-p300 Transcription Module
por: Schmidt, Thomas J., et al.
Publicado: (2022)

Src-Family Protein Kinase Inhibitors Suppress MYB Activity in a p300-Dependent Manner
por: Biyanee, Abhiruchi, et al.
Publicado: (2022)

Exosomal circ_IFT80 Enhances Tumorigenesis and Suppresses Radiosensitivity in Colorectal Cancer by Regulating miR-296-5p/MSI1 Axis
por: Li, Liang, et al.
Publicado: (2021)

Interaction of the Transactivation Domain of B-Myb with the TAZ2 Domain of the Coactivator p300: Molecular Features and Properties of the Complex
por: Oka, Ojore, et al.
Publicado: (2012)

LINC01287 regulates tumorigenesis and invasion via miR‐298/MYB in hepatocellular carcinoma
por: Mo, Yichao, et al.
Publicado: (2018)

Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis
por: Gaudino, Stephen J., et al.
Publicado: (2019)

ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein
por: Jiang, Yuying, et al.
Publicado: (2023)

Creb-Binding Protein (Cbp/P300) and RNA Polymerase II Colocalize in Transcriptionally Active Domains in the Nucleus
por: von Mikecz, Anna, et al.
Publicado: (2000)

Activation of the P38/CREB/MMP13 axis is associated with osteoarthritis
por: Ji, Bin, et al.
Publicado: (2019)

Maintenance of phosphate homeostasis and root development are coordinately regulated by MYB1, an R2R3-type MYB transcription factor in rice
por: Gu, Mian, et al.
Publicado: (2017)

MYB suppresses differentiation and apoptosis of human breast cancer cells
por: Drabsch, Yvette, et al.
Publicado: (2010)

CREB3 Transcription Factors: ER-Golgi Stress Transducers as Hubs for Cellular Homeostasis
por: Sampieri, Luciana, et al.
Publicado: (2019)

Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis
por: Miyake, Yoshiaki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uoh5oeg2g6ijs7rarfinqfrfv5