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Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells

Commitment of differentiating embryonic stem cells (ESCs) toward the various lineages is influenced by many factors, including androgens. However, the mechanisms underlying proteotoxic stress conferred by androgen receptor (AR) actions on embryonic cell fate remains unclear. Here we show that mouse...

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Detalles Bibliográficos
Autores principales: Yang, Y-C, Fu, H-C, Hsiao, B-L, Sobue, G, Adachi, H, Huang, F-J, Hsuuw, Y-D, Wei, K-T, Chang, C, Huang, K-E, Kang, H-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641345/
https://www.ncbi.nlm.nih.gov/pubmed/23618905
http://dx.doi.org/10.1038/cddis.2013.122

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