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Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells
Commitment of differentiating embryonic stem cells (ESCs) toward the various lineages is influenced by many factors, including androgens. However, the mechanisms underlying proteotoxic stress conferred by androgen receptor (AR) actions on embryonic cell fate remains unclear. Here we show that mouse...
Autores principales: | Yang, Y-C, Fu, H-C, Hsiao, B-L, Sobue, G, Adachi, H, Huang, F-J, Hsuuw, Y-D, Wei, K-T, Chang, C, Huang, K-E, Kang, H-Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641345/ https://www.ncbi.nlm.nih.gov/pubmed/23618905 http://dx.doi.org/10.1038/cddis.2013.122 |
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