The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1

In non-small cell lung cancer (NSCLC), receptor tyrosine kinases (RTKs) stand out among causal dominant oncogenes, and the ablation of RTK signaling has emerged as a novel tailored therapeutic strategy. Nonetheless, long-term RTK inhibition leads invariably to acquired resistance, tumor recurrence a...

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Detalles Bibliográficos
Autores principales: Voena, C, Di Giacomo, F, Panizza, E, D'Amico, L, Boccalatte, F E, Pellegrino, E, Todaro, M, Recupero, D, Tabbò, F, Ambrogio, C, Martinengo, C, Bonello, L, Pulito, R, Hamm, J, Chiarle, R, Cheng, M, Ruggeri, B, Medico, E, Inghirami, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641361/
https://www.ncbi.nlm.nih.gov/pubmed/23567620
http://dx.doi.org/10.1038/oncsis.2013.7

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