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A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease
Persistent eosinophil activation in both the upper and lower airway mucosa is a central feature of aspirin-exacerbated respiratory disease (AERD). Eosinophil activation and survival are profoundly influenced by interleukin 5 (IL-5) and its receptor, IL-5R. In patients susceptible to allergic disorde...
Autores principales: | Losol, Purevsuren, Kim, Seung-Hyun, Seob Shin, Yoo, Min Ye, Young, Park, Hae-Sim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641394/ https://www.ncbi.nlm.nih.gov/pubmed/23470716 http://dx.doi.org/10.1038/emm.2013.24 |
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