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ISG15: leading a double life as a secreted molecule
ISG15 is a well-known intracellular ubiquitin-like molecule involved in ISGylation. However, a recent study has revived the notion first put forward two decades ago that ISG15 is also a secreted molecule. Human neutrophils, monocytes and lymphocytes can release ISG15, even though this protein has no...
Autores principales: | Bogunovic, Dusan, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641400/ https://www.ncbi.nlm.nih.gov/pubmed/23579383 http://dx.doi.org/10.1038/emm.2013.36 |
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