MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis

Myeloid-related protein (MRP)8/MRP14 is an endogenous Toll-like receptor 4 (TLR4) ligand and is abundant in synovial fluid (SF) of rheumatoid arthritis (RA) patients. Belonging to damage-associated molecular patterns, it amplifies proinflammatory mediators and facilitates a wide range of inflammator...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Dong-Gun, Woo, Jung-Won, Kwok, Seung-Ki, Cho, Mi-La, Park, Sung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641402/
https://www.ncbi.nlm.nih.gov/pubmed/23619188
http://dx.doi.org/10.1038/emm.2013.39

Ejemplares similares

Ejemplares similares