Cargando…

Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases

The SCF (SKP1 (S-phase-kinase-associated protein 1), Cullin-1, F-box protein) E3 ubiquitin ligases, the founding member of Cullin-RING ligases (CRLs), are the largest family of E3 ubiquitin ligases in mammals. Each individual SCF E3 ligase consists of one adaptor protein SKP1, one scaffold protein c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Weihua, Wei, Wenyi, Sun, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641602/ https://www.ncbi.nlm.nih.gov/pubmed/23528706 http://dx.doi.org/10.1038/cr.2013.44

Ejemplares similares

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)(FBXW11-NSs) E3 Ligase
por: Mudhasani, Rajini, et al.
Publicado: (2016)

Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis
por: Mathur, Radhika, et al.
Publicado: (2015)

Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism
por: Emberley, Ethan D., et al.
Publicado: (2012)

The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores
por: Willhoft, Oliver, et al.
Publicado: (2017)

The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein
por: Van Rechem, Capucine, et al.
Publicado: (2011)

Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis
por: Chen, B B, et al.
Publicado: (2013)

DCUN1D3 activates SCF(SKP2) ubiquitin E3 ligase activity and cell cycle progression under UV damage
por: Zhang, Shuai, et al.
Publicado: (2016)

SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis
por: Panda, Dibyendu K., et al.
Publicado: (2022)

The SCF(Skp2) ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L)
por: Roberts, Jamie Z., et al.
Publicado: (2020)

Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases
por: Muniz, João R.C., et al.
Publicado: (2013)

SKP1-like protein, CrSKP1-e, interacts with pollen-specific F-box proteins and assembles into SCF-type E3 complex in ‘Wuzishatangju’ (Citrus reticulata Blanco) pollen
por: Ren, Yi, et al.
Publicado: (2020)

Oxygen-dependent regulation of E3(SCF)ubiquitin ligases and a Skp1-associated JmjD6 homolog in development of the social amoeba Dictyostelium
por: Boland, Andrew W., et al.
Publicado: (2022)

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival
por: Jia, Lijun, et al.
Publicado: (2009)

Regulation of SCF(TIR1/AFBs) E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling
por: Iglesias, María José, et al.
Publicado: (2018)

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL
por: Rodriguez, Sonia, et al.
Publicado: (2019)

Nonstructural protein P7-2 encoded by Rice black-streaked dwarf virus interacts with SKP1, a core subunit of SCF ubiquitin ligase
por: Wang, Qian, et al.
Publicado: (2013)

New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases
por: Canning, Peter, et al.
Publicado: (2014)

Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor
por: Aghajanyy, Mariam, et al.
Publicado: (2010)

The role of SCF ubiquitin-ligase complex at the beginning of life
por: Xie, Jiayan, et al.
Publicado: (2019)

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
por: Baek, Kheewoong, et al.
Publicado: (2023)

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
por: Baek, Kheewoong, et al.
Publicado: (2023)

The Mechanism of NEDD8 Activation of CUL5 Ubiquitin E3 Ligases
por: Lumpkin, Ryan J., et al.
Publicado: (2021)

Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p
por: Seibert, Volker, et al.
Publicado: (2002)

The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers
por: BOCHIS, OVIDIU VASILE, et al.
Publicado: (2015)

Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
por: Horn-Ghetko, Daniel, et al.
Publicado: (2021)

Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
por: Au, Wei-Chun, et al.
Publicado: (2020)

Hijacking of the Host SCF Ubiquitin Ligase Machinery by Plant Pathogens
por: Magori, Shimpei, et al.
Publicado: (2011)

SCF(β-TRCP) E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
por: Ci, Yanpeng, et al.
Publicado: (2018)

SCF(Fbxl3) Ubiquitin Ligase Targets Cryptochromes at Their Cofactor Pocket
por: Xing, Weiman, et al.
Publicado: (2013)

The SOCS-Box of HIV-1 Vif Interacts with ElonginBC by Induced-Folding to Recruit Its Cul5-Containing Ubiquitin Ligase Complex
por: Bergeron, Julien R. C., et al.
Publicado: (2010)

The Centrosomal E3 Ubiquitin Ligase FBXO31-SCF Regulates Neuronal Morphogenesis and Migration
por: Vadhvani, Mayur, et al.
Publicado: (2013)

Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
por: Cardote, Teresa A.F., et al.
Publicado: (2017)

Ubiquitination and Degradation of the Hominoid-Specific Oncoprotein TBC1D3 Is Mediated by CUL7 E3 Ligase
por: Kong, Chen, et al.
Publicado: (2012)

The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number
por: Arquint, Christian, et al.
Publicado: (2018)

The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis
por: Davidson, Jennilee M., et al.
Publicado: (2023)

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus
por: Jöhnk, Bastian, et al.
Publicado: (2016)

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases
por: Canning, Peter, et al.
Publicado: (2013)

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ
por: Lee, Kyeong Won, et al.
Publicado: (2016)

The SCF(Dia2) Ubiquitin E3 Ligase Ubiquitylates Sir4 and Functions in Transcriptional Silencing
por: Burgess, Rebecca J., et al.
Publicado: (2012)

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
por: Guan, Yongjuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qvsh0h1ibgkht33j3qg5a7ar1q