Cargando…

Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria

INTRODUCTION: Hepatitis B infection impacts negatively on disease progression in HIV infected children thereby increasing morbidity and mortality. In spite of the foregoing, there is paucity of data on Hepatitis B co-infection in children living with HIV in Owerri, South Eastern Nigeria.This study s...

Descripción completa

Detalles Bibliográficos
Autores principales: Nwolisa, Emeka, Mbanefo, Francis, Ezeogu, Joseph, Amadi, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641926/
https://www.ncbi.nlm.nih.gov/pubmed/23646225
http://dx.doi.org/10.11604/pamj.2013.14.89.1711
_version_ 1782268063029133312
author Nwolisa, Emeka
Mbanefo, Francis
Ezeogu, Joseph
Amadi, Paul
author_facet Nwolisa, Emeka
Mbanefo, Francis
Ezeogu, Joseph
Amadi, Paul
author_sort Nwolisa, Emeka
collection PubMed
description INTRODUCTION: Hepatitis B infection impacts negatively on disease progression in HIV infected children thereby increasing morbidity and mortality. In spite of the foregoing, there is paucity of data on Hepatitis B co-infection in children living with HIV in Owerri, South Eastern Nigeria.This study set out to determine the prevalence of Hepatitis B Co- infection in HIV infected children attending the Paediatric HIV Care and Treatment clinic of the Federal Medical Centre Owerri. METHODS: The study period was between February and July 2010. Testing for Hepatitis B infection was done using the ACON Hepatitis B surface antigen Rapid test strip. (Acon Laboratories Inc. San Diego.CA). RESULTS: A total of 139 HIV infected children were enrolled during the study period. The overall prevalence of Hepatitis B Co- infection was 5.8% (8/139). The prevalence in males was 8.2% (5/61) while in females it was 3.8% (3/78). The prevalence of Hepatitis B Co- infection amongst patients on antiretroviral therapy was 4.6%. They accounted for 62.5% of Hepatitis B Co- infection in our study. Previous blood transfusion, gender and age of patient did not show statistically significant relationship with Hepatitis B Co-infection. CONCLUSION: Though our study shows a low prevalence of Hepatitis B co infection in HIV infected children in our centre, reduction of the rate is still strongly desirable. Reduction can be achieved by strengthing the uptake of Hepatitis B vaccine as part of the routine childhood immunization programme.
format Online
Article
Text
id pubmed-3641926
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-36419262013-05-03 Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria Nwolisa, Emeka Mbanefo, Francis Ezeogu, Joseph Amadi, Paul Pan Afr Med J Research INTRODUCTION: Hepatitis B infection impacts negatively on disease progression in HIV infected children thereby increasing morbidity and mortality. In spite of the foregoing, there is paucity of data on Hepatitis B co-infection in children living with HIV in Owerri, South Eastern Nigeria.This study set out to determine the prevalence of Hepatitis B Co- infection in HIV infected children attending the Paediatric HIV Care and Treatment clinic of the Federal Medical Centre Owerri. METHODS: The study period was between February and July 2010. Testing for Hepatitis B infection was done using the ACON Hepatitis B surface antigen Rapid test strip. (Acon Laboratories Inc. San Diego.CA). RESULTS: A total of 139 HIV infected children were enrolled during the study period. The overall prevalence of Hepatitis B Co- infection was 5.8% (8/139). The prevalence in males was 8.2% (5/61) while in females it was 3.8% (3/78). The prevalence of Hepatitis B Co- infection amongst patients on antiretroviral therapy was 4.6%. They accounted for 62.5% of Hepatitis B Co- infection in our study. Previous blood transfusion, gender and age of patient did not show statistically significant relationship with Hepatitis B Co-infection. CONCLUSION: Though our study shows a low prevalence of Hepatitis B co infection in HIV infected children in our centre, reduction of the rate is still strongly desirable. Reduction can be achieved by strengthing the uptake of Hepatitis B vaccine as part of the routine childhood immunization programme. The African Field Epidemiology Network 2013-03-07 /pmc/articles/PMC3641926/ /pubmed/23646225 http://dx.doi.org/10.11604/pamj.2013.14.89.1711 Text en © Emeka Nwolisa et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Nwolisa, Emeka
Mbanefo, Francis
Ezeogu, Joseph
Amadi, Paul
Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title_full Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title_fullStr Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title_full_unstemmed Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title_short Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
title_sort prevalence of hepatitis b co-infection amongst hiv infected children attending a care and treatment centre in owerri, south-eastern nigeria
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641926/
https://www.ncbi.nlm.nih.gov/pubmed/23646225
http://dx.doi.org/10.11604/pamj.2013.14.89.1711
work_keys_str_mv AT nwolisaemeka prevalenceofhepatitisbcoinfectionamongsthivinfectedchildrenattendingacareandtreatmentcentreinowerrisoutheasternnigeria
AT mbanefofrancis prevalenceofhepatitisbcoinfectionamongsthivinfectedchildrenattendingacareandtreatmentcentreinowerrisoutheasternnigeria
AT ezeogujoseph prevalenceofhepatitisbcoinfectionamongsthivinfectedchildrenattendingacareandtreatmentcentreinowerrisoutheasternnigeria
AT amadipaul prevalenceofhepatitisbcoinfectionamongsthivinfectedchildrenattendingacareandtreatmentcentreinowerrisoutheasternnigeria