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Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

BACKGROUND: The p53 protein is the best studied target in human cancer. For decades, p53 has been believed to act mainly as a tumor suppressor and by transcriptional regulation. Only recently, the complex and diverse function of p53 has attracted more attention. Using several molecular approaches, w...

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Detalles Bibliográficos
Autores principales:	Wachter, Franziska, Grunert, Michaela, Blaj, Cristina, Weinstock, David M, Jeremias, Irmela, Ehrhardt, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641951/ https://www.ncbi.nlm.nih.gov/pubmed/23594441 http://dx.doi.org/10.1186/1478-811X-11-27

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