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Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria
BACKGROUND: Human cerebral malaria (HCM) is a life-threatening complication caused by Plasmodium falciparum infection that continues to be a major global health problem despite optimal anti-malarial treatment. In the experimental model of cerebral malaria (ECM) by Plasmodium berghei ANKA, bolus admi...
Autores principales: | Martins, Yuri C, Clemmer, Leah, Orjuela-Sánchez, Pamela, Zanini, Graziela M, Ong, Peng Kai, Frangos, John A, Carvalho, Leonardo JM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642006/ https://www.ncbi.nlm.nih.gov/pubmed/23617605 http://dx.doi.org/10.1186/1475-2875-12-138 |
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