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Critical Role of TLR7 Signaling in the Priming of Cross-Protective Cytotoxic T Lymphocyte Responses by a Whole Inactivated Influenza Virus Vaccine

Current influenza vaccines fail to induce protection against antigenically distinct virus strains. Accordingly, there is a need for the development of cross-protective vaccines. Previously, we and others have shown that vaccination with whole inactivated virus (WIV) induces cross-protective cellular...

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Detalles Bibliográficos
Autores principales: Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Waijer, Simke, Boon, Louis, Gostick, Emma, Price, David A., Wilschut, Jan, Huckriede, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642048/
https://www.ncbi.nlm.nih.gov/pubmed/23658804
http://dx.doi.org/10.1371/journal.pone.0063163