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Critical Role of TLR7 Signaling in the Priming of Cross-Protective Cytotoxic T Lymphocyte Responses by a Whole Inactivated Influenza Virus Vaccine
Current influenza vaccines fail to induce protection against antigenically distinct virus strains. Accordingly, there is a need for the development of cross-protective vaccines. Previously, we and others have shown that vaccination with whole inactivated virus (WIV) induces cross-protective cellular...
Autores principales: | Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Waijer, Simke, Boon, Louis, Gostick, Emma, Price, David A., Wilschut, Jan, Huckriede, Anke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642048/ https://www.ncbi.nlm.nih.gov/pubmed/23658804 http://dx.doi.org/10.1371/journal.pone.0063163 |
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