A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization

Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins. Herein, we describe the cloning, expression, refolding an...

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Detalles Bibliográficos
Autores principales: Ferrer, Valéria Pereira, de Mari, Thiago Lopes, Gremski, Luiza Helena, Trevisan Silva, Dilza, da Silveira, Rafael Bertoni, Gremski, Waldemiro, Chaim, Olga Meiri, Senff-Ribeiro, Andrea, Nader, Helena Bonciani, Veiga, Silvio Sanches
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642055/
https://www.ncbi.nlm.nih.gov/pubmed/23658852
http://dx.doi.org/10.1371/journal.pntd.0002206

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