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Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells
There is concern regarding neurotoxicity induced by the use of local anesthetics. A previous study showed that an overload of intracellular calcium is involved in the neurotoxic effect of some anesthetics. T-type calcium channels, which lower the threshold of action potentials, can regulate the infl...
Autores principales: | Wen, Xianjie, Xu, Shiyuan, Liu, Hongzhen, Zhang, Quinguo, Liang, Hua, Yang, Chenxiang, Wang, Hanbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642072/ https://www.ncbi.nlm.nih.gov/pubmed/23658789 http://dx.doi.org/10.1371/journal.pone.0062942 |
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